Researchers at Michigan Medicine have uncovered a key mechanism that regulates blood pressure and vascular remodeling in people with a genetic variant linked to high blood pressure.

Researchers have discovered a new molecular process that occurs when donor hearts are preserved in cold storage which contributes to failure after transplant, a study in both humans and animals shows. Fortunately, therapy that is typically prescribed for high blood pressure can target this process to reduce cold preservation associated with cardiac injury. This discovery has potential to improve the consistent function of donor hearts and extend the distance they can be safely transported in cold storage.

A study finds most hospitals don’t see many cardiogenic shock patients. When they do, providers often do not have a standardized way of treating them.

A compound that was previously found to treat severe fatty liver disease also reduces atherosclerosis, a primary driver of cardiovascular death, in non-human primates. The drug candidate was developed at the University of Michigan.

There are over six million Americans with heart failure who are at greater risk of losing their cognitive abilities earlier in life, a study led by University of Michigan suggests. 

Stroke survivors who have attended some level of higher education may face even steeper mental declines, according to a study led by Michigan Medicine.

People with diabetes often have a host of other conditions including cardiovascular disease and kidney disease driven by inflammation. On today's episode, we talk with Dr. Katherine Gallagher, professor of surgery, professor of microbiology and immunology, and the Leland Ira Doan Research Professor of Vascular Surgery at U of M, who is looking at how epigenetics - the influence of environmental factors and behaviors impact on gene expression - might explain changes in the immune system in people with cardiovascular disease, diabetes, and other conditions related to inflammation.

A young man from Michigan who was born with the rare disease Barth Syndrome received a new heart over two decades after having a heart transplant as an infant.

A Michigan Medicine doctor discusses how e-cigarettes and vaping harm your health and cardiovascular system.

After four lifesaving heart surgeries, teen plays in Junior League World Series, shares journey to benefit other children with congenital heart disease.

According to findings by Michigan Medicine, one in five older patients gets an infection up to six months following heart surgery — with women much more likely to develop one.

A famous sports announcer for University of Michigan football finds himself getting heart care at Michigan Medicine and spreading the word to others to be proactive about their heart health.

Despite the success cardiac rehabilitation has shown at reducing heart-related deaths and hospital readmissions, higher out-of-pocket costs may prevent patients from participating in the program, a University of Michigan study suggests. 

For people taking the popular blood thinners rivaroxaban (brand name Xarelto) and apixaban (brand name Eliquis), after having a blood clot, a reduced dose may limit the future risk of bleeding as well as hospital visits, a Michigan Medicine-led study suggests.

Michigan Medicine's team of cardiology experts offered an advanced, minimally invasive coronary intervention, which restored one patient back to good health